Discoveries that improve human health and welfare
THE KU LIFE SPAN INSTITUTE brings together scientists and students at the intersections of education, behavioral science and neuroscience to study problems that directly affect the health and well-being of individuals and communities in Kansas, as well as across the nation and world.
investigators, students and staff
million awarded for research in FY2019
of improving human health and welfare
Profile: Matthew Mosconi
Early diagnosis of neurodevelopmental disorders such as autism spectrum disorder is critical to providing access to early intervention and other therapies that have a direct impact on the child's future quality of life. Autism is diagnosed using behavioral standards as we still do not fully understand the genetics and other factors that may cause autism.
That's one reason Matthew Mosconi focuses his research on understanding the development of behavioral and cognitive issues characteristic of autism spectrum disorder and specifically, identifying the brain mechanisms that lead to them.
Mosconi is the director of the Kansas Center for Autism Research and Treatment (K-CART), and director of the Neurobehavioral Development Laboratory, both at the University of Kansas. In this interview, he looks back at his first four years with K-CART and shares his aspirations for autism research at KU.
How would you describe your experience at KU?
A major appeal of KU was the great potential for collaborating with leading behavioral researchers interested in autism spectrum disorder (ASD), and the strong reputation of the Life Span Institute for fostering collaborative and productive research. The reality has exceeded my expectations. People here are very eager to support each other’s work and identify collaborative opportunities. It is difficult to create and maintain an environment that actively promotes high impact research without making investigators compete with each other or experience a shark-tank type of environment – KU and the Life Span Institute have skillfully struck and maintained this balance.
Findings: Omega-3 fatty acids
Few things are as important in a baby’s first year of life as nutrition – that’s a given. But new research suggests that increasing intake of an omega-3 fatty acid while pregnant has a positive effect on the fetus that continues to affect the child’s development years later.
A team of scientists at the KU Life Span Institute recently authored a study that showed that pregnant women who consumed a supplement of DHA (docosahexaenoic acid), a nutrient added to U.S. infant formulas since 2002, tend to have children with higher fat-free body mass at 5 years old. The findings of the experimental study, presented in the most recent issue of the American Journal of Clinical Nutrition, suggest that improving maternal DHA nutrition has a favorable programming effect on the fetus that influences body composition in early childhood.
“DHA is a nutrient found in the highest concentrations in oily fish such as salmon and tuna, foods many Americans don’t eat a lot of, so they tend to get low intakes,” said Susan Carlson, professor in the Department of Dietetics & Nutrition in the School of Health Professions. “Because U.S. intakes are low and because DHA is highly concentrated in the brain where it increases dramatically in the last trimester of pregnancy and the first two years of life, I have had a long interest in whether more of this nutrient is needed for optimal health during early development. DHA can be delivered to the fetus by increasing maternal intake during pregnancy and to the breast-fed infant by increasing maternal intake during lactation, which increases DHA in mothers’ milk.”
Program: Transition to Post-Secondary Education
When Noah Krueger came to KU in the fall of 2016, one of the first challenges to overcome was learning how the KU bus system worked. Like any KU freshman student unaccustomed to public transit, he struggled at first with figuring out which bus went where and when.
But two years after starting a program for students with intellectual disabilities, he can not only check off success at navigating the bus system, he said. He has completed two years of classes at KU and grown academically and socially – and he can teach other people how to ride the bus, too.
“The bus was a big deal,” Noah said. “But now I’ve learned living on my own, grocery shopping, budgeting, working, and living with friends.”
Noah is just one of the 18 students who are enrolled in or have completed a two-year certificate at KU through the Transition to Postsecondary Education program. Funded through a five-year federal grant to the Life Span Institute in 2015, and in collaboration with the KU School of Education, the program is the only one of its kind in Kansas that combines career development, academics and social skills for students with intellectual disabilities.
The 2019 freshman class in the program have diverse education backgrounds, experiences and interests, including working with children, athletics, musical theater, and interior design.
Sept. 13 3-4:30 pm Open House
Join us for an open house celebrating the first year of achievements of the Cofrin Logan Center, 3061 Dole
Sept. 19 4-5:00 pm K-CART Seminar
Kansas Center for Autism Research and Training fall seminar: James Bartolotti, PhD., from University of Kansas-Lawrence
A new study in the Journal of Neurophysiology by researchers at the University of Kansas Life Span Institute is the first to look at functional brain activity in people with autism spectrum disorder (ASD) while they performed precision visuomotor behavior — in this case, a grip-force test.
The authors found new evidence sensorimotor changes in people with autism involve abnormal cortical and subcortical organization “that may contribute to key clinical issues in patients.”
When Rosemarie Truglio was growing up in Hoboken, New Jersey, “Romper Room” was the closest thing to educational programming on television. Like other children across the country, she waited for the host of that "live kindergarten" program to hold up her magic mirror and call out the names of children who might be watching at home. Unlike most other children, she would go on to work in groundbreaking educational children’s programming with Sesame Workshop, the nonprofit organization behind “Sesame Street.”